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The 1998 death of Katie Couric's husband, Jay Monahan, spurred her to become an advocate, co-founding the National Colorectal Cancer Research Alliance (NCCRA) with the Entertainment Industry Foundation (EIF) eight years ago. Fund-raising efforts led by Katie have since generated more than $30 million. Due to NCCRA grants, scientists conducting cutting-edge research have made significant advances, and the death rate from colon cancer fell almost 10 percent between 2003 and 2005. Katie is also working with the University of Virginia to establish the Emily Couric Clinical Cancer Center, named for her sister, who died of pancreatic cancer.

Sherry Lansing is the founder and current chair of the Sherry Lansing Foundation, a philanthropic organization focused on cancer research and education. The chair of Paramount Pictures' Motion Picture Group from 1992 to 2005, Sherry currently serves on the boards of Friends of Cancer Research, The Lasker Foundation and Stop Cancer. Sherry lost her mother to ovarian cancer.

Laura Ziskin has been a motion picture and television producer for 25 years. As the founding president of Fox 2000, she shepherded such films as 'The Thin Red Line' and 'Fight Club'; other film credits include 'Pretty Woman' and the 'Spider-Man' trilogy. Like one in three U.S. women, Laura was diagnosed with cancer (Stage 3 breast cancer) in 2004. As a cancer survivor, she is determined to make cancer a first-tier issue in this country.

Formerly VP of corporate communications for International Creative Management, Ellen co-founded Rob Reiner's I Am Your Child Foundation in 1994. In 2005 she began working as a marketing consultant for the Skoll Foundation, which invests in worldwide social entrepreneurs. This year, Ellen became a partner in the Global Philanthropy Group, which works with high net-worth individuals, charitable foundations and corporations to design and implement philanthropic strategies. Ellen's mother is a lymphoma survivor.

Samuel Goldwyn and other Hollywood luminaries pooled the industry's charitable resources in 1942, and the organization that became the Entertainment Industry Foundation (EIF) was born. Since then, EIF has raised $300 million for cancer research and prevention, diabetes awareness, and arts- and music-education programs. People from every facet of entertainment -- actors and executives, guild and union members and employees of studios, networks and talent agencies -- volunteer their talent and services to the foundation. In the fight against cancer, EIF raises critically needed dollars for research and treatment, fast-tracks the most promising science and generates awareness.

The Noreen Fraser Foundation was created in 2006 by Noreen and Woody Fraser and co-created by Rusty Robertson and Sue Schwartz to raise awareness and funding to find a cure for women's cancers. Specifically, the organization acts to change the funding model for cancer research. The NFF distributes larger sums of money to fewer scientists and researchers, with the belief that such a structure better provides these brilliant minds the time, tools and environment to eradicate a disease which has taken the lives of so many.

Founded in 1907, the American Association for Cancer Research is the world's oldest and largest professional organization dedicated to advancing research to prevent and cure cancer. The membership includes nearly 27,000 researchers, healthcare professionals and cancer survivors and advocates in the United States and more than 70 other countries. AACR marshals the full spectrum of expertise from the cancer community to provide quality scientific and educational programs and six major peer-reviewed journals. The AACR also publishes CR, a magazine for cancer survivors, patient advocates, their families and physicians.